Reverse Anti-Aging Serum
Our premium formula targets wrinkles and fine lines, firming and rejuvenating your skin while diminishing your pores for a more youthful, age-defying appearance.
(30 days)
15%+ Savings on
all Subscriptions
Free Shipping on
Orders over $99
1-Year Money-
Back Guarantee
WHY Reverse Anti-Aging Serum
We all treasure the wisdom and confidence that accompanies our years. Unfortunately, the visible signs of aging – fine lines, uneven dry skin, loss of firmness – often tell a story we'd prefer to rewrite. That's why we developed Reverse Anti-Aging Serum, a formula designed to reduce fine lines, boost collagen and return your skin's glow without using the harsh, synthetic ingredients found in other anti-aging products.
At the heart of our formula are two patented complexes – Croda Juvinity™, clinically proven to boost collagen production by 483%, and Croda PoreTect™, which contains a naturally-occurring peptide that calms and soothes while reducing inflammation – alongside Tremella mushroom, whose ultra-fine hydration molecules penetrate all three dermal layers for profound moisture. These work synergistically with antioxidants, omega fatty acids, and natural anti-inflammatory ingredients to create a holistic, science-backed approach to skin rejuvenation.
Unlike many anti-aging serums that fade within hours and deliver little long-term change, our Reverse Anti-Aging Serum gives your skin instant hydration that lasts all day. With regular use, you'll notice visible, long-lasting improvements in firmness and smooth skin. And because we're confident, you'll love your results, we back every bottle with an industry-first 365-day money-back guarantee
BENEFITS
- Deep hydration to all 3 layers of your skin.*
- Speeds up skin cell regeneration to bring new, healthy, younger-looking cells to the surface.*
- Patented ingredients increase cellular collagen production to help "fill-in" facial lines and deep wrinkles. Clinical studies showed depth of wrinkles decreased as much as 15% in 4 weeks.*
- Helps provide deep, long-lasting hydration for a plump, dewy look.*
- Supports softer, smoother skin texture and a natural moisture barrier.*
- Offers antioxidant-rich defense against daily environmental stressors.*
- Promotes a firmer, more supple feel over time with consistent use.*
PRODUCT DETAILS
- Suggested Usage Amount: 1 full pump
- # of Pumps: Approx. 150
- Form: Liquid/Oil
- Product Size: 1 fluid ounce bottle (30 ml)
- Protective 1 oz. Glass bottle
- Vegan Friendly & Animal cruelty-free
- NO toxic chemicals frequently found in beauty products such as preservatives, parabens, phthalates, or sulfates
- Animal-cruelty-free (not tested on animals)
- 3rd-party lab tested. Results reveal no hidden GMOs, herbicides, pesticides, or heavy metals
Made With:
-
Croda Juvinity™
A targeted skin care ingredient designed to help reduce the visible signs of aging for a more youthful appearance.
-
Croda Poretect™
Developed to help refine the look of skin texture and support the appearance of improved firmness.
-
Tremella Mushroom Extract (Tremella Fuciformis Extract)
A hydrating botanical that helps support a smoother, more supple skin appearance.
-
Organic Cranberry Seed Oil (Organic Vaccinium Macrocarpon)
A lightweight oil that helps condition the skin and support a soft, nourished feel.
-
Raspberry Seed Oil (Rubus Idaeus)
Helps moisturize and support the skin's natural barrier for a healthy-looking complexion.
-
Argan Stem Cells (Argania Spinosa Sprout Cell Extract)
Plant-derived extract that helps support the skin's natural vitality and a revitalized look.
Resources
EWG Ratings: EWG staff review each product's type, composition, and claims using ingredient labels and scientific data, then assign a safety rating based on nearly 60 toxicity and regulatory databases. Each ingredient is rated on a scale of 1 - 10, 1 being very clean and 10 being highly toxic. Find out more at https://www.ewg.org/skindeep/
Dr. Melissa Gallagher,
Naturopathic Physician
From a clinical perspective, effective anti-aging skincare should do more than simply moisturize the surface of the skin—it should support cellular resilience, collagen signaling, and optimal hydration of the skin barrier.
Reverse Anti-Aging Serum formulation reflects a multifactorial approach to skin aging: protecting cells from oxidative damage, stimulating structural proteins such as collagen, and improving hydration at the epidermal level. From a clinical standpoint, ingredients that support both the extracellular matrix and the skin barrier are particularly valuable in anti-aging formulations. With consistent use, a serum built around these evidence-supported mechanisms help the skin appear firmer, smoother, and more resilient, making it a powerful tool in your effort to reverse visible signs of aging.
Read Less Read More
Reverse Anti-Aging Serum incorporates ingredients that address several of these biological pathways. One of the most notable actives in the formulation is Juvinity™, a longevity-focused ingredient studied for its ability to protect skin cells from oxidative stress and improve extracellular matrix function.
Research evaluating this compound has demonstrated a reduction in intracellular oxidative stress of approximately 85%, along with significant increases in structural skin components, including collagen synthesis (up to 483%), decorin production (~32%), and hyaluronic acid synthesis (~33%). In controlled cosmetic testing panels, these cellular improvements translated into visible clinical outcomes, including reductions in wrinkle depth of roughly 26% after four weeks of use. (source)
Another ingredient that contributes to the clinical rationale of this serum is Tremella fuciformis (snow mushroom) extract, a polysaccharide-rich botanical known for its exceptional water-binding and skin-conditioning properties.
Studies evaluating Tremella-derived polysaccharides in cosmetic formulations have demonstrated significant improvements in epidermal hydration and a reduction in transepidermal water loss (TEWL) of approximately 12%, indicating enhanced barrier integrity. Maintaining hydration and barrier integrity critical because dehydrated skin exaggerates the appearance of fine lines and accelerates visible aging.(source)
Daily Use
Apply once or twice a day after cleansing and toning, but before applying moisturizer. Take a small amount (one pump) and massage gently into the skin of your face and neck with your fingertips. Can be used under makeup.
Advanced Use
Consistently apply twice per day to face, neck, and dècolletè (area around the neckline).
Pairs Well With
If beautiful, younger-looking skin is your priority, consider pairing with Restore Vitamin C Serum - scientifically formulated to promote healthy collagen & elastin production for firmer skin.
Croda Juvinity™
A unique, patented skin formula designed to help smooth wrinkles and restructure the dermis. Juvinity™ protects skin cells from UV overexposure that can lead to DNA damage, and repairs cells below the skin's surface. In lab tests it increased collagen production by 483% and improved cellular metabolism significantly.
Tremella Mushroom Extract (Tremella Fuciformis Extract)
Known as the "beauty mushroom", tremella is packed with natural plant collagen and its gel-like structure can hold up to 500 times its own weight in water. With hydration particles even smaller than hyaluronic acid, it's able to penetrate and deliver nutrients to all 3 layers of the skin.
Organic Cranberry Seed Oil (Organic Vaccinium Macrocarpon Seed Oil)
Cranberry is the only known fruit oil that's balanced in omega oils 3, 6, and 9, allowing it to sink deep into the layers of the skin to moisturize and protect, without leaving skin feeling heavy or greasy. It also contains high levels of antioxidants and phytosterols that can support collagen production.
Organic Raspberry Seed Oil (Organic Rubus Idaeus Seed Oil)
The small but mighty seeds from fresh raspberry fruit are cold pressed to produce an anti-inflammatory oil packed with vitamins A, C, and E. Raspberry seed is a highly stable oil that resists oxidation and is prized for helping to keep skin hydrated, plump, and free from fine lines and wrinkles.
Argan Stem Cells Sprout (Argania Spinosa Sprout Cell Extract)
Argan stem cells come from the famed argan tree. They can penetrate into the dermis layer of skin to soothe and heal and can even act as a catalyst for revitalizing human skin stem cells. In a clinical study of volunteers under 50, wrinkle depth and appearance dropped a significant 26% in under two months of argan stem cell use.
Hide View 8 ingredients
Apple Stem Cells Extract (Malus Domestica Fruit Cell Culture)
Helps support skin's natural renewal process, promoting a smoother, more youthful-looking appearance. Rich in antioxidant properties, it helps protect skin from environmental stressors while supporting firmness and vitality.
Sunflower Seed Oil (Helianthus Annuus)
Is rich in essential fatty acids and vitamin E, helping to nourish, soften, and support the skin's natural moisture barrier. Its lightweight, non-greasy feel helps lock in hydration while supporting smooth, healthy-looking skin.
Rose Geranium Essential Oil (Pelargonium Graveolens Essential Oil)
Rich in antioxidants, rose geranium is a natural antifungal, antimicrobial, and anti-inflammatory oil known for its ability to soothe and heal many skin ailments including dermatitis, eczema, psoriasis, oily skin, and acne. It can also fade scars and stretch marks and help reduce the appearance of fine lines and wrinkles.
Polyglyceryl-4 Oleate
A gentle, plant-derived emulsifier that helps blend oil and water while supporting a smooth, stable formula. It enhances skin feel by helping products spread easily.
Caprylyl Glycol
A skin-conditioning ingredient that helps hydrate and soften the skin while also supporting the stability and shelf life of skincare formulations. It sourced from plant-based fatty acids, and is valued for being gentle, multifunctional, and suitable for a wide range of skin types.
Pentylene Glycol
Made using plant-based sugars through a gentle fermentation process. It helps keep skin feeling hydrated while improving the overall feel and performance of a skincare formula, and is valued for being both effective and skin-friendly.
Ethylhexylglycerin
Comes from plant-based glycerin and fatty acids. It helps keep skin feeling soft and smooth while also supporting the overall effectiveness of our skincare formula. It's valued for being gentle, multifunctional, and well suited for sensitive skin types.
Propanediol
Helps to draw moisture into the skin while improving the texture and feel of our skincare formula. It is made from plant-based sugars through a sustainable fermentation process and is valued for being gentle, effective, and suitable for all skin types, including sensitive skin.
Resources
EWG Ratings: EWG staff review each product's type, composition, and claims using ingredient labels and scientific data, then assign a safety rating based on nearly 60 toxicity and regulatory databases. Each ingredient is rated on a scale of 1 - 10, 1 being very clean and 10 being highly toxic. Find out more at https://www.ewg.org/skindeep/
Reverse is an anti-wrinkle serum formulated for use on all skin types, and specifically for aging skin (approximately ages 40+). As with all skincare products, a patch test is recommended before using. If you notice any irritation, discontinue use. Reverse also pares really well with Restore Vitamin C Serum for added healing benefits.
We offer a 1-Year Money-Back Guarantee so if for any reason the product doesn't work for you, you can send the bottle back and receive a full refund.
If you use one (1) pump of serum a day the bottle will last a full 30 days. To ensure uninterrupted use, every 30 days, take advantage of our 15% off auto-ship subscription option.
Reverse can be used daily (once or twice a day) indefinitely, if desired. The best way to ensure uninterrupted use is by taking advantage of our 15% off auto-ship subscription option.
Restore Vitamin C Serum is a water-based serum that is beneficial for all adult skin types and ages (i.e., ages 20+). You can think of it like a multivitamin for your skin that also helps to prevent and repair facial wrinkles and skin damage. Restore also increases skin elasticity, and smooths, brightens, and tightens skin.
Reverse Anti-Aging Serum is an oil-based anti-wrinkle serum with all of the ingredients geared specifically to anti-aging (ages 40+). This hydrating and nourishing anti-aging face serum will penetrate the skin and provide plumping and firming action and a youthful glow.
Both products are amazing individually and even better when used together. You can choose to use the Restore in the morning and Reverse at night. Or, for maximum benefit, use both together. To use both you would first apply the Restore Vitamin C Serum, let it dry, and then apply Reverse Anti-Aging Serum.
Both products are amazing individually and even better when used together. You can choose to use the Restore in the morning and Reverse at night. Or, for maximum benefit, use both together. To use both you would first apply the Restore Vitamin C Serum, let it dry, and then apply Reverse Anti-Aging Serum.
Reverse should be applied to clean skin. If you're using other products, apply it AFTER cleansing and toning, but BEFORE moisturizing. We recommend waiting a minute or two after you apply Reverse to allow it to penetrate your skin before applying your eye cream, moisturizer, and/or makeup.
Reverse Anti-Aging Serum is both vegan and animal-cruelty-free (not tested on animals). We encourage you to check out our certified test results here and... take a peek at which animal LOVES our products.
EWG Ratings: EWG staff review each product's type, composition, and claims using ingredient labels and scientific data, then assign a safety rating based on nearly 60 toxicity and regulatory databases. Each ingredient is rated on a scale of 1 - 10, 1 being very clean and 10 being highly toxic. Find out more at https://www.ewg.org/skindeep/
Still have questions?
Our Customer Success team is ready to help.
Visit contact.gorgias.help/en-US/forms/59ct283n or call 877-750-6455.
Monday-Saturday: 9am - 6pm ET
CUSTOMER REVIEWS
1-Year Money-Back Guarantee
1-Year Money-Back Guarantee
Safe, Clean, Non-gmo Ingredients
Most skincare products on the market are made with toxic chemicals and harsh filler ingredients that have the potential to damage your sensitive skin cells. At AnnieMak, we're proud to offer the absolute best, safest, and cleanest skincare products to help protect and enhance your skin's natural radiance. Our products are made with non-GMO ingredients, made by mother nature to help your skin look and feel years younger... naturally!
People Over Profits
We believe in doing things differently. While most skincare companies spend most of their money on advertising, we spend hours on the highest-quality, clean, and non-GMO ingredients available - organic, whenever possible. In fact, we spend on average 400% (4 times) more to manufacture our products. In the end, you get exactly what you pay for – the best skincare products on the market.
Patented Formulas
Our skincare products contain unique, patented formulas, proven in evidence-based lab studies to help protect your skin at the foundational level. These safe, non-toxic, and innovative formulations work synergistically with our naturally healing ingredients to help give you smoother, healthier-looking skin, no matter what your age is.
Skincare You Can Trust
Since there are really no agencies or regulators looking over the shoulder of the skincare industry, it can be hard, even impossible to know who to trust. Left to police themselves, many companies cut corners to boost their bottom line. But we are committed to providing customers with third-party tested, truly clean products for a difference they can feel on their skin. It's a harder, more difficult, and much more expensive process to source clean ingredients... but we think your skin is worth it!
Manufactured in the U.S.A.
All our products are manufactured in the U.S.A. at an FDA-registered, CGMP-compliant facility. The vast majority of the individual ingredients that we use in our skincare products are grown in and sourced right here in the U.S. The few ingredients sourced from other countries are indigenous to those regions, with ZERO of our ingredients being sourced from China.
Our Results Speak for Themselves
Thousands of health-conscious customers like you use and trust Organixx Clean Skincare products as a part of their daily skincare routine. We've received hundreds of 5-Star reviews and also received a LOT of overjoyed feedback from folks sharing how pleased they are to finally find a skincare company 100% committed to using the purest, non-GMO, and healthy ingredients.
Organixx is Helping 80,000
Mothers & Children in 2026
Purchasing Organixx supplements does more than just support the health of you and your family... it also helps pregnant women, breastfeeding mothers and children under five who are at risk of malnutrition... right here in the U.S. and around the globe. We are proud to partner with Vitamin Angels, a global public health nutrition organization. For over 25 years Vitamin Angels has promoted maternal and child health by ensuring vulnerable, underserved populations have access to lifesaving and life-changing vitamins and minerals. This year alone, Organixx's financial support will allow Vitamin Angels to assist 80,000 children and mothers in 70 countries and all 50 states. Thank you for helping us do even more good in the world!